mindmap root((厌烦)) annoy implies a wearing on the nerves by persistent and often petty unpleasantness: his constant complaining ~s us. vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety: a problem that ~es cancer researchers. irk stresses difficulty in enduring and resulting weariness or impatience: his chronic tardiness ~s his colleagues. bother suggests bewildering or upsetting interference with comfort or peace of mind: that discrepancy ~s me.